KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRM1L
All Species:
26.97
Human Site:
T197
Identified Species:
65.93
UniProt:
Q7Z2T5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z2T5
NP_112196.3
733
81747
T197
S
A
T
I
T
R
R
T
D
M
L
G
H
V
R
Chimpanzee
Pan troglodytes
XP_514058
733
81738
T197
S
A
T
I
T
R
R
T
D
M
L
G
H
V
R
Rhesus Macaque
Macaca mulatta
XP_001113820
735
82068
T199
S
A
T
I
T
R
R
T
D
M
L
G
H
V
R
Dog
Lupus familis
XP_849853
735
81848
T199
S
A
T
I
T
R
R
T
D
M
L
G
H
V
R
Cat
Felis silvestris
Mouse
Mus musculus
A2RSY6
728
80843
T194
S
A
T
I
T
R
R
T
D
M
L
G
H
V
K
Rat
Rattus norvegicus
Q496Z9
723
80166
T190
S
A
T
I
T
R
R
T
D
M
L
G
H
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516176
726
80805
T180
S
A
T
I
T
R
R
T
D
M
V
G
H
I
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090259
648
72911
H163
T
L
K
E
L
N
T
H
V
Q
V
S
P
N
F
Zebra Danio
Brachydanio rerio
XP_688031
693
77496
R175
D
M
I
S
H
L
K
R
H
I
N
K
G
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796695
468
52054
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.2
94.2
N.A.
87.9
87
N.A.
68.7
N.A.
54.7
55.6
N.A.
N.A.
N.A.
N.A.
27.4
Protein Similarity:
100
99.4
98.9
97
N.A.
92.3
91.8
N.A.
79.9
N.A.
69.7
71.3
N.A.
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
70
10
0
0
% G
% His:
0
0
0
0
10
0
0
10
10
0
0
0
70
0
0
% H
% Ile:
0
0
10
70
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
20
% K
% Leu:
0
10
0
0
10
10
0
0
0
0
60
0
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
70
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
70
70
10
0
0
0
0
0
0
40
% R
% Ser:
70
0
0
10
0
0
0
0
0
0
0
10
0
0
10
% S
% Thr:
10
0
70
0
70
0
10
70
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
10
0
20
0
0
60
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _